Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

Abstract Background Airway remodelling is the major pathological feature of chronic obstructive pulmonary disease (COPD), and leads to poorly reversible airway obstruction. Current pharmacological interventions are ineffective in controlling airway remodelling. In the present study, we investigated...

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Bibliographic Details
Main Authors: Kunming Pan, Juanjuan Lu, Yun Song
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Respiratory Research
Subjects:
Artesunate
COPD
Airway remodelling
Cigarette smoke
PPAR-γ
Online Access:https://doi.org/10.1186/s12931-021-01687-y

Internet

https://doi.org/10.1186/s12931-021-01687-y

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