The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant <i>Aspergillus Fumigatus</i> Harboring TR<sub>34</sub>/L98H Via Asexual Reproduction

The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant <i>Aspergillus Fumigatus</i> Harboring TR<sub>34</sub>/L98H Via Asexual Reproduction

Azole-resistant <i>Aspergillus fumigatus</i> isolates recovered at high frequency from patients, harbor mutations that are associated with variation of promoter length in the <i>cyp51A</i> gene. Following the discovery of the TR<sub>34</sub>/L98H genotype, new var...

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Bibliographic Details
Main Authors: Jianhua Zhang, Jan Zoll, Tobias Engel, Joost van den Heuvel, Paul E. Verweij, Alfons J. M. Debets
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Fungi
Subjects:
azole resistance
tandem repeats variants
asexual reproduction
<i>Aspergillus fumigatus</i>
antifungal agents
Online Access:https://www.mdpi.com/2309-608X/6/4/277

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https://www.mdpi.com/2309-608X/6/4/277

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