TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults

Abstract Brain damage due to stroke or traumatic brain injury (TBI), both leading causes of serious long-term disability, often leads to the development of epilepsy. Patients who develop post-injury epilepsy tend to have poor functional outcomes. Emerging evidence highlights a potential role for blo...

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Bibliographic Details
Main Authors: Soo Young Kim, Vladimir V. Senatorov, Christapher S. Morrissey, Kristina Lippmann, Oscar Vazquez, Dan Z. Milikovsky, Feng Gu, Isabel Parada, David A. Prince, Albert J. Becker, Uwe Heinemann, Alon Friedman, Daniela Kaufer
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07394-3