Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Drug resistance is a major problem in cancer chemotherapy. Acquisition of chemo-resistance not only reduces the effectiveness of drugs, but also promotes side effects and markedly reduces the patient's quality of life. However,...

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Main Authors: Sato Yuji, Oshima Takahiro, Sun Bailong, Kamiyama Naoya, Kudo Takeaki, Takahashi Masato, Nakagawa Hiroaki, Hamaguchi Jun, Deguchi Kisaburo, Todo Satoru, Nishimura Shin-Ichiro
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/58