Blocking premature reverse transcription fails to rescue the HIV-1 nucleocapsid-mutant replication defect
<p>Abstract</p> <p>Background</p> <p>The nucleocapsid (NC) protein of HIV-1 is critical for viral replication. Mutational analyses have demonstrated its involvement in viral assembly, genome packaging, budding, maturation, reverse transcription, and integration. We prev...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-06-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/8/1/46 |