CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections

CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections

Visualization of infection and the associated host response has been challenging in adult vertebrates. Owing to their transparency, zebrafish larvae have been used to directly observe infection in vivo; however, such larvae have not yet developed a functional adaptive immune system. Cells involved i...

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Bibliographic Details
Main Authors: Mark R. Cronan, Allison F. Rosenberg, Stefan H. Oehlers, Joseph W. Saelens, Dana M. Sisk, Kristen L. Jurcic Smith, Sunhee Lee, David M. Tobin
Format: Article
Language:English
Published: The Company of Biologists 2015-12-01
Series:Disease Models & Mechanisms
Subjects:
Zebrafish
Infection
PACT
CLARITY
Imaging
Mouse
Tuberculosis
Mycobacteria
Online Access:http://dmm.biologists.org/content/8/12/1643

Internet

http://dmm.biologists.org/content/8/12/1643

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