KDM1A microenvironment, its oncogenic potential, and therapeutic significance

KDM1A microenvironment, its oncogenic potential, and therapeutic significance

Abstract The lysine-specific histone demethylase 1A (KDM1A) was the first demethylase to challenge the concept of the irreversible nature of methylation marks. KDM1A, containing a flavin adenine dinucleotide (FAD)-dependent amine oxidase domain, demethylates histone 3 lysine 4 and histone 3 lysine 9...

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Bibliographic Details
Main Authors: Tayaba Ismail, Hyun-Kyung Lee, Chowon Kim, Taejoon Kwon, Tae Joo Park, Hyun-Shik Lee
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Epigenetics & Chromatin
Subjects:
Histone demethylation
Carcinogenesis
Acute myeloid leukemia
KDM1A
TLL
Online Access:http://link.springer.com/article/10.1186/s13072-018-0203-3

Internet

http://link.springer.com/article/10.1186/s13072-018-0203-3

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