Ginsenoside Rh2 suppresses growth of uterine leiomyoma in vitro and in vivo and may regulate ERα/c-Src/p38 MAPK activity

Ginsenoside Rh2 suppresses growth of uterine leiomyoma in vitro and in vivo and may regulate ERα/c-Src/p38 MAPK activity

Panax ginseng is widely used as a functional food in Asia because of its bioactivities. Here, we report that ginsenoside Rh2, an extract of red Panax ginseng, suppressed growth of uterine leiomyomas (ULs) in a rat model and decreased serum hormone levels in a dose-dependent manner. Rh2 also inhibite...

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Bibliographic Details
Main Authors: Yan Zhu, Junjiu Xu, Zhao Li, Shuwu Xie, Jieyun Zhou, Xiangjie Guo, Xianying Zhou, Guoting Li, Ruihua Zhong, Aying Ma
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Ginsenoside Rh2
ERα
c-Src
p38 MAPK
Uterine leiomyoma
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003515

Internet

http://www.sciencedirect.com/science/article/pii/S1756464615003515

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