TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production
<p>Abstract</p> <p>Background</p> <p>Metastasis is the primary cause of death for cancer patients. TWIST1, an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor, is a strong promoter of metastatic spread and its expression is elevated in many ad...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1741-7007/10/73 |