Intratumoral LIGHT Restores Pericyte Contractile Properties and Vessel Integrity

Normalization of the tumor vasculature is an emerging concept shown to improve anti-cancer therapy. However, there are currently no clinical interventions that effect long-lasting normalization. Here, we have developed a strategy for normalization by specific intratumoral delivery of LIGHT/TNFSF14....

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Bibliographic Details
Main Authors: Anna Johansson-Percival, Zhi-Jie Li, Devina D. Lakhiani, Bo He, Xiao Wang, Juliana Hamzah, Ruth Ganss
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014163