Modelling primaquine-induced haemolysis in G6PD deficiency

Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd). As testing for G6PDd is often unavailable, this li...

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Bibliographic Details
Main Authors: James Watson, Walter RJ Taylor, Didier Menard, Sim Kheng, Nicholas J White
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/23061