Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis

Abstract Background Rapid advances in the past decade have shown that dysbiosis of the gut microbiome is a key hallmark of rheumatoid arthritis (RA). Yet, the relationship between the gut microbiome and clinical improvement in RA disease activity remains unclear. In this study, we explored the gut m...

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Bibliographic Details
Main Authors: Vinod K. Gupta, Kevin Y. Cunningham, Benjamin Hur, Utpal Bakshi, Harvey Huang, Kenneth J. Warrington, Veena Taneja, Elena Myasoedova, John M. Davis, Jaeyun Sung
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genome Medicine
Subjects:
Rheumatoid arthritis
Gut microbiome
Clinical disease activity index
Minimum clinically important improvement
Shotgun metagenomic sequencing
Machine-learning
Online Access:https://doi.org/10.1186/s13073-021-00957-0

Internet

https://doi.org/10.1186/s13073-021-00957-0

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