Generate TALE/TALEN as Easily and Rapidly as Generating CRISPR
TALE has always had potential as a gene-editing and regulatory tool. However, with the advent of CRISPR/Cas9, an easier to use tool with the same function, TALE has recently been abandoned because of the time-consuming and low-efficiency process required for its construction. The off-target activity...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-06-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S232905011930021X |