New variants in NLRP3 inflammasome genes increase risk for asthma and Blomia tropicalis-induced allergy in a Brazilian population

New variants in NLRP3 inflammasome genes increase risk for asthma and Blomia tropicalis-induced allergy in a Brazilian population

Atopic asthma is a chronic lung disease of lower airways caused mainly due to action of T-helper (Th) 2 type cytokines, eosinophilic inflammation, mucus hypersecretion and airway remodelling. Interleukin (IL)-33 increases type 2 immunity polarization in airway playing critical role in eosinophilic a...

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Bibliographic Details
Main Authors: Gerson de A. Queiroz, Raimon R. da Silva, Anaque de O. Pires, Ryan dos S. Costa, Neuza M. Alcântara-Neves, Thiago M. da Silva, Mauricio L. Barreto, Sergio C. Oliveira, Camila A. Figueirêdo
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Cytokine: X
Subjects:
Asthma
Allergy
Inflammasome
Variants
NLRP3
CASP1
Online Access:http://www.sciencedirect.com/science/article/pii/S2590153220300124

Internet

http://www.sciencedirect.com/science/article/pii/S2590153220300124

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