New variants in NLRP3 inflammasome genes increase risk for asthma and Blomia tropicalis-induced allergy in a Brazilian population
Atopic asthma is a chronic lung disease of lower airways caused mainly due to action of T-helper (Th) 2 type cytokines, eosinophilic inflammation, mucus hypersecretion and airway remodelling. Interleukin (IL)-33 increases type 2 immunity polarization in airway playing critical role in eosinophilic a...
Main Authors: | Gerson de A. Queiroz, Raimon R. da Silva, Anaque de O. Pires, Ryan dos S. Costa, Neuza M. Alcântara-Neves, Thiago M. da Silva, Mauricio L. Barreto, Sergio C. Oliveira, Camila A. Figueirêdo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Cytokine: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590153220300124 |
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