Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination.

Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination.

Both Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) establish the persistent, life-long infection primarily at the latent status, and associate with certain types of tumors, such as B cell lymphomas, especially in immuno-compromised individuals including people livi...

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Bibliographic Details
Main Authors: Ayan Biswas, Dawei Zhou, Guillaume N Fiches, Zhenyu Wu, Xuefeng Liu, Qin Ma, Weiqiang Zhao, Jian Zhu, Netty G Santoso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009764

Internet

https://doi.org/10.1371/journal.ppat.1009764

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