Dysregulation of the EphrinB2−EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients

Blood vessels: untangling the causes of brain vessel malformations Tangled blood vessel growths in the brain, known as arteriovenous malformations (AVMs), can be identified with a urine test, and the test protein may also help in treatment. AVMs often have no symptoms and can go undiagnosed, but whe...

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Bibliographic Details
Main Authors: Katie Pricola Fehnel, David L. Penn, Micah Duggins-Warf, Maxwell Gruber, Steven Pineda, Julie Sesen, Alexander Moses-Gardner, Nishali Shah, Jessica Driscoll, David Zurakowski, Darren B. Orbach, Edward R. Smith
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0414-0