Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches

Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches

Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to overcome resistance. For such combination therapi...

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Bibliographic Details
Main Authors: Ameeta eAgarwal, Siddharth eTripathi, Tao eXu, Melissa eJacob, Xing-Cong eLi, Alice eClark
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Microbiology
Subjects:
genetic interaction
chemogenomic profiling
drug synergy mechanism
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00115/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00115/full

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