Synthesis and Facile Dearomatization of Highly Electrophilic Nitroisoxazolo[4,3-<i>b</i>]pyridines

A number of novel 6-R-isoxazolo[4,3-<i>b</i>]pyridines were synthesized and their reactions with neutral C-nucleophiles (1,3-dicarbonyl compounds, π-excessive (het)arenes, dienes) were studied. The reaction rate was found to be dependent on the nature of the substituent 6-R. The most rea...

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Bibliographic Details
Main Authors: Maxim A. Bastrakov, Alexey K. Fedorenko, Alexey M. Starosotnikov, Ivan V. Fedyanin, Vladimir A. Kokorekin
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/9/2194