Adenosine A2A receptor blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism

Pharmacological studies implicate the blockade of adenosine receptorsas an effective strategy for reducing Parkinson's disease (PD) symptoms. The objective of this study is to elucidate the possible protective effects of ZM241385 and 8-cyclopentyl-1,3-dipropylxanthine, two selective A2Aand A1 r...

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Bibliographic Details
Main Authors: Ahmed M Fathalla, Amira M Soliman, Mohammed H Ali, Ahmed A. Moustafa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00035/full