NK Cell Precursors in Human Bone Marrow in Health and Inflammation

NK Cell Precursors in Human Bone Marrow in Health and Inflammation

NK cells are generated from hematopoietic stem cells (HSC) residing in the bone marrow (BM), similar to other blood cells. Development toward mature NK cells occurs largely outside the BM through travel of CD34+ and other progenitor intermediates toward secondary lymphoid organs. The BM harbors mult...

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Bibliographic Details
Main Authors: Federica Bozzano, Carola Perrone, Lorenzo Moretta, Andrea De Maria
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
NK cells
CD34+ precursors
inflammation
common lymphoid precursor
DNAM-1
CXCR4
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02045/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02045/full

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