A Comparative Cytotoxic Evaluation of Disulfiram Encapsulated PLGA Nanoparticles on MCF-7 Cells

Background: Disulfiram is oral aldehyde dehydrogenase (ALDH) inhibitor that has been used in the treatment of alcoholism. Recent studies show that this drug has anticancer properties; however, its rapid degradation has limited its clinical application. Encapsulation of disulfiram polymeric nanoparti...

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Bibliographic Details
Main Authors: Hamidreza Fasehee, Ardeshir Ghavamzadeh, Kamran Alimoghaddam, Seyed H. Ghaffari, Shahab Faghihi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-04-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/571