Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner.

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner.

Hepatitis C virus (HCV) induces interferon (IFN) stimulated genes in the liver despite of distinct innate immune evasion mechanisms, suggesting that beyond HCV infected cells other cell types contribute to innate immune activation. Upon coculture with HCV replicating cells, human CD141+ myeloid dend...

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Bibliographic Details
Main Authors: Stephanie Pfaender, Elena Grabski, Claudia N Detje, Nina Riebesehl, Stefan Lienenklaus, Eike Steinmann, Ulrich Kalinke, Thomas Pietschmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4934921?pdf=render

Internet

http://europepmc.org/articles/PMC4934921?pdf=render

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