Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

Abstract Background Docetaxel-based chemotherapy failure in advanced prostate carcinoma has partly been attributed to the resistance of prostate cancer (PC) cells to docetaxel-induced apoptosis. Hence, there is an urgent need to identify mechanisms of docetaxel chemoresistance and to develop new com...

Full description

Bibliographic Details
Main Authors: Zhan Yang, Jin-Suo Chen, Jin-Kun Wen, Hai-Tao Gao, Bin Zheng, Chang-Bao Qu, Kai-Long Liu, Man-Li Zhang, Jun-Fei Gu, Jing-Dong Li, Yan-Ping Zhang, Wei Li, Xiao-Lu Wang, Yong Zhang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-193a-5p
Prostate cancer
Docetaxel
Chemoresistance
HO-1
Bach2
Online Access:http://link.springer.com/article/10.1186/s13046-017-0649-3

Internet

http://link.springer.com/article/10.1186/s13046-017-0649-3

Similar Items