Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer.

Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer.

Pro-inflammatory cytokinemia is a hallmark of highly pathogenic H5N1 influenza virus (IAV) disease yet little is known about the role of host proteins in modulating a pathogenic innate immune response. The host Interferon Induced Protein 35 (Ifi35) has been implicated in increased susceptibility to...

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Bibliographic Details
Main Authors: Anshu P Gounder, Christine C Yokoyama, Nicholas N Jarjour, Traci L Bricker, Brian T Edelson, Adrianus C M Boon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5940246?pdf=render

Internet

http://europepmc.org/articles/PMC5940246?pdf=render

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