Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers

Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers

Abstract Background The Centiloid scale has been developed to standardize measurements of amyloid PET imaging. Reference cut-off values of this continuous measurement enable the consistent operationalization of decision-making for multicentre research studies and clinical trials. In this study, we a...

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Main Authors: Gemma Salvadó, José Luis Molinuevo, Anna Brugulat-Serrat, Carles Falcon, Oriol Grau-Rivera, Marc Suárez-Calvet, Javier Pavia, Aida Niñerola-Baizán, Andrés Perissinotti, Francisco Lomeña, Carolina Minguillon, Karine Fauria, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, for the Alzheimer’s Disease Neuroimaging Initiative, for the ALFA Study
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
AD pathophysiology
Biomarker concordance
Threshold
Positivity
Preclinical
Early detection
Online Access:http://link.springer.com/article/10.1186/s13195-019-0478-z

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http://link.springer.com/article/10.1186/s13195-019-0478-z

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