Cognitive and socio-emotional deficits in platelet-derived growth factor receptor-β gene knockout mice.

Platelet-derived growth factor (PDGF) is a potent mitogen. Extensive in vivo studies of PDGF and its receptor (PDGFR) genes have reported that PDGF plays an important role in embryogenesis and development of the central nervous system (CNS). Furthermore, PDGF and the β subunit of the PDGF receptor (...

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Main Authors: Phuong Thi Hong Nguyen, Tomoya Nakamura, Etsuro Hori, Susumu Urakawa, Teruko Uwano, Juanjuan Zhao, Ruixi Li, Nguyen Duy Bac, Takeru Hamashima, Yoko Ishii, Takako Matsushima, Taketoshi Ono, Masakiyo Sasahara, Hisao Nishijo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060876?pdf=render