Regulation of caveolin and caveolae by cholesterol in MDCK cells

We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis, or β-trimethyl cyclodextrin (CD), a cholestero...

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Bibliographic Details
Main Authors: Deborah Hailstones, Leanne S. Sleer, Robert G. Parton, Keith K. Stanley
Format: Article
Language:English
Published: Elsevier 1998-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338980