Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.

Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.

Ixodes ticks are major vectors for human pathogens, such as Borrelia burgdorferi, the causative agent of Lyme disease. Tick saliva contains immunosuppressive molecules that facilitate tick feeding and B. burgdorferi infection. We here demonstrate, to our knowledge for the first time, that the Ixodes...

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Bibliographic Details
Main Authors: Joppe W R Hovius, Marein A W P de Jong, Jeroen den Dunnen, Manja Litjens, Erol Fikrig, Tom van der Poll, Sonja I Gringhuis, Teunis B H Geijtenbeek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18282094/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18282094/?tool=EBI

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