Phenotypic and Functional Characterization of Double Negative B Cells in the Blood of Individuals With Obesity

We have previously shown that obesity is associated with increased secretion of IgG antibodies with anti-self-reactivity. In this paper, we confirm and extend our previous findings. We show that the plasma of individuals with obesity is enriched in autoimmune antibodies whose levels are positively a...

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Bibliographic Details
Main Authors: Daniela Frasca, Alain Diaz, Maria Romero, Bonnie B. Blomberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.616650/full