Synthesis and evaluation of bisulfate/mesylate-conjugated chlortetracycline with high solubility and bioavailability

The aim of this work is to improve the solubility and bioavailability of chlortetracycline and the function of the immune response. Chlortetracycline bisulfate and chlortetracycline mesylate were successfully synthesized and characterized with several techniques, including spectroscopy, chromatograp...

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Bibliographic Details
Main Authors: Liu Deng, Chen Peixing, Yang Xu, Wang Jianhua
Format: Article
Language:English
Published: Sciendo 2020-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2020-0041