Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma

Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma

Abstract Background Inclusion of new biomarkers to improve a personalized treatment approach for oropharyngeal squamous cell carcinoma (OPSCC) is urgently needed. Hypomethylation of the Long interspersed nucleotide element-1 (LINE-1) repetitive elements, a widely accepted surrogate of overall genomi...

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Bibliographic Details
Main Authors: Carlo Furlan, Jerry Polesel, Luigi Barzan, Giovanni Franchin, Sandro Sulfaro, Salvatore Romeo, Francesca Colizzi, Aurora Rizzo, Vittorio Baggio, Vittorio Giacomarra, Angelo Paolo Dei Tos, Paolo Boscolo-Rizzo, Emanuela Vaccher, Riccardo Dolcetti, Luca Sigalotti, Elisabetta Fratta
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Clinical Epigenetics
Subjects:
Oropharyngeal squamous cell carcinoma
DNA methylation
LINE-1
HPV
Online Access:http://link.springer.com/article/10.1186/s13148-017-0357-z

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http://link.springer.com/article/10.1186/s13148-017-0357-z

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