Extracorporeal IgE Immunoadsorption in Allergic Asthma: Safety and Efficacy

Extracorporeal IgE Immunoadsorption in Allergic Asthma: Safety and Efficacy

Background: Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column (IgEnio). IgEnio is based on a recombinant, IgE-s...

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Bibliographic Details
Main Authors: Christian Lupinek, Kurt Derfler, Silvia Lee, Thomas Prikoszovich, Oliver Movadat, Eva Wollmann, Carolin Cornelius, Milena Weber, Renate Fröschl, Regina Selb, Katharina Blatt, Dubravka Smiljkovic, Volker Schoder, René Cervenka, Thomas Plaichner, Gottfried Stegfellner, Hans Huber, Rainer Henning, Justyna Kozik-Jaromin, Thomas Perkmann, Verena Niederberger, Ventzislav Petkov, Peter Valent, Adelheid Gauly, Hans Peter Leinenbach, Ingrid Uhlenbusch-Koerwer, Rudolf Valenta
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:EBioMedicine
Subjects:
Allergy
Asthma
Immunoadsorption
IgEnio
IgE
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641730066X

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http://www.sciencedirect.com/science/article/pii/S235239641730066X

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