Glycerol not lactate is the major net carbon source for gluconeogenesis in mice during both short and prolonged fasting

Objective: Fasting results in major metabolic changes including a switch from glycogenolysis to gluconeogenesis to maintain glucose homeostasis. However, the relationship between the length of fasting and the relative contribution of gluconeogenic substrates remains unclear. We investigated the rela...

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Bibliographic Details
Main Authors: Yujue Wang, Hyokjoon Kwon, Xiaoyang Su, Fredric E. Wondisford
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309342