Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment

Tubal ectopic pregnancies are a leading cause of global maternal morbidity and mortality. Previous infection with Chlamydia trachomatis is a major risk factor for tubal embryo implantation but the biological mechanism behind this association is unclear. Successful intra-uterine embryo implantation i...

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Bibliographic Details
Main Authors: Syed F. Ahmad, Jeremy K. Brown, Lisa L. Campbell, Magda Koscielniak, Catriona Oliver, Nick Wheelhouse, Gary Entrican, Stuart McFee, Gillian S. Wills, Myra O. McClure, Patrick J. Horner, Sevasti Gaikoumelou, Kai F. Lee, Hilary O.D. Critchley, W. Colin Duncan, Andrew W. Horne
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418300744