The Role of Taste Receptors in Airway Innate Immune Defense

The Role of Taste Receptors in Airway Innate Immune Defense

Bitter (T2R) and sweet (T1R) taste receptors are expressed in the upper airway, where they play key roles in antimicrobial innate immune defense. Bitter bacterial products are detected by taste receptors on ciliated cells and solitary chemosensory cells, resulting in downstream nitric oxide and anti...

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Bibliographic Details
Main Authors: Alan D. Workman, Neil N. Patel, Ryan M. Carey, Edward C. Kuan, Noam A. Cohen
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Sinusitis
Subjects:
taste receptors
solitary chemosensory cell
taste test
T2R
T1R
Online Access:http://www.mdpi.com/2309-107X/3/2/6

Internet

http://www.mdpi.com/2309-107X/3/2/6

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