Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual

Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual

In recent years, improved sequencing technology and computational tools have made de novo genome assembly more accessible. Many approaches, however, generate either an unphased or only partially resolved representation of a diploid genome, in which polymorphisms are detected but not assigned to one...

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Bibliographic Details
Main Authors: llya Soifer, Nicole L. Fong, Nelda Yi, Andrea T. Ireland, Irene Lam, Matthew Sooknah, Jonathan S. Paw, Paul Peluso, Gregory T. Concepcion, David Rank, Alex R. Hastie, Vladimir Jojic, J. Graham Ruby, David Botstein, Margaret A. Roy
Format: Article
Language:English
Published: Oxford University Press 2020-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
haplotype
phased genome
phased sequencing
chromosome sorting
human genome
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400995

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400995

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