Multiple Myeloma Cells Express Key Immunoregulatory Cytokines and Modulate the Monocyte Migratory Response

Multiple Myeloma Cells Express Key Immunoregulatory Cytokines and Modulate the Monocyte Migratory Response

Multiple myeloma (MM) is a plasma cell disorder that still remains incurable. The immune dysfunction of the host is a striking characteristic of MM, leading to tumor growth and reducing the survival rate of patients. Monocytes are precursors of conventional dendritic cells (DCs), a major player in t...

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Bibliographic Details
Main Authors: Leonardo Freire-de-Lima, Ana Flávia Fernandes Ribas Nardy, Erivan Schnaider Ramos-Junior, Luciana Conde, Jéssica Santos Lemos, Leonardo Marques da Fonseca, Juliana Echevarria Lima, Angelo Maiolino, Alexandre Morrot
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Medicine
Subjects:
multiple myeloma
monocytes
leukocyte migration
immune response
immunoregulation
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00092/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2017.00092/full

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