DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues.

DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues.

Whole-genome copy number analysis platforms, such as array comparative genomic hybridization (aCGH) and single nucleotide polymorphism (SNP) arrays, are transformative research discovery tools. In cancer, the identification of genomic aberrations with these approaches has generated important diagnos...

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Bibliographic Details
Main Authors: Justin M Craig, Natalie Vena, Shakti Ramkissoon, Ahmed Idbaih, Shaun D Fouse, Memet Ozek, Aydin Sav, D Ashley Hill, Linda R Margraf, Charles G Eberhart, Mark W Kieran, Andrew D Norden, Patrick Y Wen, Massimo Loda, Sandro Santagata, Keith L Ligon, Azra H Ligon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3376148?pdf=render

Internet

http://europepmc.org/articles/PMC3376148?pdf=render

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