Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

Several biologically relevant phospholipids were assessed as potential carriers/additives for rapidly dissolving solid formulations of piroxicam (Biopharmaceutics Classification System Class II drug). On the basis of in vitro dissolution studies, dimyristoylphosphatidylglycerol (DMPG) was ranked as...

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Bibliographic Details
Main Authors: Muhammad D. Hussain, Inna Miroshnyk, James F. Brausch, Muhammad J. Habib, Sabiruddin Mirza
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Pharmaceutics
Subjects:
poorly water soluble drugs
phospholipids
solid dispersions
dissolution
bioavailability
Online Access:http://www.mdpi.com/1999-4923/2/4/339/

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http://www.mdpi.com/1999-4923/2/4/339/

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