Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

Monocytes/macrophages are an influential component of the glioma microenvironment. However, understanding their diversity and plasticity constitute one of the most challenging areas of research due to the paucity of models to study these cells' inherent complexity. Herein, we analyzed the role...

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Bibliographic Details
Main Authors: Konrad Gabrusiewicz, Mohammad B. Hossain, Nahir Cortes-Santiago, Xuejun Fan, Bozena Kaminska, Frank C. Marini, Juan Fueyo, Candelaria Gomez-Manzano
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615000433