Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p

Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p

Abstract Background Although gemcitabine-based chemotherapy has been established as a core multimodal therapy for non-small cell lung cancer (NSCLC) treatment, its clinical efficacy remains limited by the development of acquired resistance following tumor metastasis and relapse. In this study, we in...

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Bibliographic Details
Main Authors: Feng Wei, Chengyuan Ma, Tong Zhou, Xuechao Dong, Qinghua Luo, Li Geng, Lijuan Ding, Yandong Zhang, Li Zhang, Nan Li, Yang Li, Yan Liu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Molecular Cancer
Subjects:
Exosome
Gemcitabine-resistant
Malignant phenotypic traits
miR-222-3p
Non-small cell lung cancer
Online Access:http://link.springer.com/article/10.1186/s12943-017-0694-8

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http://link.springer.com/article/10.1186/s12943-017-0694-8

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