Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction

Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction

Ebola virus (EBOV) is an enveloped, ssRNA virus from the family Filoviridae capable of causing severe hemorrhagic fever with up to 80–90% mortality rates. The most recent outbreak of EBOV in West Africa starting in 2014 resulted in over 11,300 deaths; however, long-lasting persistence and recurrence...

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Bibliographic Details
Main Authors: Michelle L. Pleet, Allison Mathiesen, Catherine DeMarino, Yao A. Akpamagbo, Robert A. Barclay, Angela Schwab, Sergey Iordanskiy, Gavin C. Sampey, Benjamin Lepene, Philipp A. Ilinykh, Alexander Bukreyev, Sergei Nekhai, M. Javad Aman, Fatah Kashanchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Microbiology
Subjects:
Ebola virus
EBOV
VP40
VLP
exosomes
ESCRT
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2016.01765/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2016.01765/full

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