Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

<p>Abstract</p> <p>Background</p> <p>Childhood hospitalization related to asthma remains at historically high levels, and its incidence is on the rise world-wide. Previously, we have demonstrated that aldose reductase (AR), a regulatory enzyme of polyol pathway, is a ma...

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Bibliographic Details
Main Authors: Yadav Umesh CS, Aguilera-Aguirre Leopoldo, Boldogh Istvan, Ramana Kota V, Srivastava Satish K
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Respiratory Research
Subjects:
Online Access:http://respiratory-research.com/content/12/1/145