Cardiovascular phenotype of the Dmdmdx rat – a suitable animal model for Duchenne muscular dystrophy

Cardiovascular phenotype of the Dmdmdx rat – a suitable animal model for Duchenne muscular dystrophy

Besides skeletal muscle abnormalities, Duchenne muscular dystrophy (DMD) patients present with dilated cardiomyopathy development, which considerably contributes to morbidity and mortality. Because the mechanisms responsible for the cardiac complications in the context of DMD are largely unknown, ev...

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Bibliographic Details
Main Authors: Petra Lujza Szabó, Janine Ebner, Xaver Koenig, Ouafa Hamza, Simon Watzinger, Sandra Trojanek, Dietmar Abraham, Hannes Todt, Helmut Kubista, Klaus Schicker, Séverine Remy, Ignacio Anegon, Attila Kiss, Bruno K. Podesser, Karlheinz Hilber
Format: Article
Language:English
Published: The Company of Biologists 2021-02-01
Series:Disease Models & Mechanisms
Subjects:
muscular dystrophy
remodeling
cardiovascular dysfunction
cardiomyocyte
rat
Online Access:http://dmm.biologists.org/content/14/2/dmm047704

Internet

http://dmm.biologists.org/content/14/2/dmm047704

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