Identification of highly connected and differentially expressed gene subnetworks in metastasizing endometrial cancer.

We have identified nine highly connected and differentially expressed gene subnetworks between aggressive primary tumors and metastatic lesions in endometrial carcinomas. We implemented a novel pipeline combining gene set and network approaches, which here allows integration of protein-protein inter...

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Bibliographic Details
Main Authors: Kanthida Kusonmano, Mari K Halle, Elisabeth Wik, Erling A Hoivik, Camilla Krakstad, Karen K Mauland, Ingvild L Tangen, Anna Berg, Henrica M J Werner, Jone Trovik, Anne M Øyan, Karl-Henning Kalland, Inge Jonassen, Helga B Salvesen, Kjell Petersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6211718?pdf=render