Oral vitamin D supplementation induces transcriptomic changes in rectal mucosa that are linked to anti-tumour effects

Oral vitamin D supplementation induces transcriptomic changes in rectal mucosa that are linked to anti-tumour effects

Abstract Background The risk for several common cancers is influenced by the transcriptomic landscape of the respective tissue-of-origin. Vitamin D influences in vitro gene expression and cancer cell growth. We sought to determine whether oral vitamin D induces beneficial gene expression effects in...

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Bibliographic Details
Main Authors: P. G. Vaughan-Shaw, G. Grimes, J. P. Blackmur, M. Timofeeva, M. Walker, L. Y. Ooi, Victoria Svinti, Kevin Donnelly, F. V. N. Din, S. M. Farrington, M. G. Dunlop
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Medicine
Subjects:
Vitamin D
Colorectal cancer
Gene expression
Biomarker
Online Access:https://doi.org/10.1186/s12916-021-02044-y

Internet

https://doi.org/10.1186/s12916-021-02044-y

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