Doxorubicin Delivery Using pH and Redox Dual-Responsive Hollow Nanocapsules with a Cationic Electrostatic Barrier

Doxorubicin Delivery Using pH and Redox Dual-Responsive Hollow Nanocapsules with a Cationic Electrostatic Barrier

For the delivery of doxorubicin (DOX), pH and redox dual responsive hollow nanocapsules were prepared through the stabilization of polymer vesicles, which spontaneously formed from polyamidoamine dendron-poly(l-lysine) (PAMAM dendron-PLL), by the introduction of disulfide (SS) bonds between PLLs. Th...

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Bibliographic Details
Main Authors: Ryoma Teranishi, Ryota Matsuki, Eiji Yuba, Atsushi Harada, Kenji Kono
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Pharmaceutics
Subjects:
hollow nanocapsules
doxorubicin
dual responsive
electrostatic barrier
drug delivery system
self-assembled polymers
Online Access:http://www.mdpi.com/1999-4923/9/1/4

Internet

http://www.mdpi.com/1999-4923/9/1/4

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