Significance of the Genomic Landscape of a De Novo Endocrine-Resistant Metastatic Hormone Receptor–Positive Breast Cancer

Endocrine therapy with or without CDK4/6 inhibitors is the most commonly used frontline treatment option for metastatic hormone receptor–positive breast cancer. Approximately, 25% to 30% of women may have resistance to endocrine therapy, especially in the setting of certain genomic mutations in the...

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Bibliographic Details
Main Authors: Maithreyi Sarma, Yara Abdou, Ajay Dhakal, Shipra Gandhi
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.1177/1178223420976387