iPSC-Derived Embryoid Bodies as Models of c-<i>Met</i>-Mutated Hereditary Papillary Renal Cell Carcinoma

iPSC-Derived Embryoid Bodies as Models of c-<i>Met</i>-Mutated Hereditary Papillary Renal Cell Carcinoma

Hereditary cancers with cancer-predisposing mutations represent unique models of human oncogenesis, as a driving oncogenic event is present in germline. Currently, there are no satisfactory models to study these malignancies. We report the generation of IPSC from the somatic cells of a patient with...

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Bibliographic Details
Main Authors: Jin Wook Hwang, Christophe Desterke, Olivier Féraud, Stephane Richard, Sophie Ferlicot, Virginie Verkarre, Jean Jacques Patard, Julien Loisel-Duwattez, Adlen Foudi, Frank Griscelli, Annelise Bennaceur-Griscelli, Ali G Turhan
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
hereditary papillary renal cell carcinoma
c-<i>met</i> mutation
induced pluripotent stem cell
kidney cancer organoids
Online Access:https://www.mdpi.com/1422-0067/20/19/4867

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https://www.mdpi.com/1422-0067/20/19/4867

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